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Saturday, 7 January 2017

Arava (leflunomide)

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LeflunomideInformation :

ARAVA is indicated in adults for the treatment of active rheumatoid arthritis (RA):

to reduce signs and symptoms

to inhibit structural damage as evidenced by X-ray erosions and joint space narrowing

to improve physical function

INSTRUCTIONS

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

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The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

STORAGE

Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F). Protect from light. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Store the medicine in a closed container at room temperature, away from heat, moisture.

Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Store the medicine in a closed container at room temperature, away from heat, moisture.

SIDE EFFECTS OF Arava (leflunomide)

In addition to its needed effects, some unwanted effects may be caused by leflunomide. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking leflunomide:

More common

Bloody or cloudy urine
cough
difficult or painful breathing
difficult, burning, or painful urination
dizziness
fever
frequent urge to urinate
headache
loss of appetite
nausea or vomiting
sneezing
sore throat
tightness in the chest
yellow eyes or skin

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Less common

Burning feeling in the chest or stomach
burning, prickling, or tingling sensation in the fingers or toes
chest pain
diarrhea
fast heartbeat
indizestion
joint or muscle pain or stiffness
pounding heartbeat
severe stomach pain

Incidence not known

Area rash
black or tarry stools
bleeding gums
blistering, peeling, or loosening of the skin
bloating
blood in the stools
burning, numbness, tingling, or painful sensations
chills
clay-colored stools
confusion
constipation
continuing vomiting
cough or hoarseness
dark urine
fainting
fever with or without chills
general feeling of tiredness or weakness
high fever

Some of the side effects that can occur with leflunomide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Premarin (Conjugated Estrogens)

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PREMARIN (CONJUGATED ESTROGENS)

Premarin Information

Premarin is a member of the Conjugated Estrogens group of drugs, based on the female sex hormone estrogen. Estrogen is a hormone essential to the female physiology, on which many of the female-specific body function are based. Among the disorders that may occur when the estrogen quantity becomes insufficient, some examples are: menopause, infertility, and someBreast Cancer types, and ovary function deficiencies, degeneration of the vagina or urethra. The male human body also needs estrogen to function properly, insufficient quantities of this hormone leading to prostate cancer.

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Premarin Indications

Premarin is mainly prescribed for the treatment of such disorders as:

moderate or severe vasomotor symptoms associated with the menopause
moderate or severe symptoms of vaginal or vulvar atrophy associated with the menopause
hypoestrogenism due to hypogonadism, castration or primary ovarian failure
some types of Breast Cancer
advanced androgen-dependent carcinoma of the prostate
prevention of postmenopausal osteoporosis – in carefully selected cases.

There are a number of other cases in which Premarin can be prescribed, so if you want to know more about why you have been prescribed this drug, consult your personal health care specialist.

Premarin Warnings

Consult with your personal health care specialist before starting to take Premarin if you are suffering of blood clotting and circulation disorders, abnormal vaginal bleedings, cancer of the breast, uterus or any type of hormone-dependent cancer, as treatment with Premarin might be dangerous in such cases. Also, special care, monitoring or altered dosages may be required for patients that are suffering or have medical history of:

Uterine fibroids
Gall bladder diseases
Diabetes
Migraines
Epilepsy
Asthma

This drug has been in a number of cases considered to be the main cause of malformed fetus development. Use of this drug is hazardous to an unborn child, so you should never take Premarin if you are pregnant or planning to become a mother soon. Also, Premarin may affect breast milk flow and composition, so it is advised that you should consult with your personal health care specialist before starting on this drug if you are a nursing mother.
It is also strongly advised that Premarin be prescribed at the lowest dosage and for the shortest time possible, as prolonged treatment or high dosage of this medicine can cause a number of other hormone related diseases.

Premarin Dosage

Consult your personal health care specialist to obtain the Premarin dosage best suited to your age and general health condition. Self-medication should never be employed when starting a treatment with this medicine. Never alter the dosage you have been given by your physician, either by modifying the drug quantity or the time interval between intakes.

Premarin Overdose

While it is very unlikely that Premarin overdose will result in fatal consequences, it is recommended that you immediately seek emergency medical care if you suspect you are suffering from an overdose with this drug and / or have unusual symptoms. The most common symptoms of Premarin overdose are nausea, vomiting and vaginal bleeding.

Premarin Missed Dose

You should set up a strict time schedule for your Premarin intakes, to prevent dose omission. However, should you happen to miss a dose, do not take a double dose to make up for the lost one, instead just return to your normal schedule.

Premarin Side Effects

One of the most serious side effects associated with Premarin treatment is the increased risk of developing cancer of the uterus, through development of endometrial hyperplasia. However, this effect can be countered by taking progestins.
Other serious side effects of Premarin use are:

If you are under treatment with any of these drugs, or have recently finished treatment with any of them, please talk with your personal health care specialist as he may decide to alter your Premarin dosage and / or keep you under special monitoring for the duration of the treatment.

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Valtrex (Valacyclovir)

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Valtrex (VALACYCLOVIR) is an antiviral drug. It slows the growth and spread of the herpes virus so that the body can fight off the infection. Valtrex (VALACYCLOVIR) will not cure herpes, but it can lessen the symptoms of the infection.Valtrex (VALACYCLOVIR) is used to treat infections caused by herpes viruses in adults and children. Illnesses caused by herpes viruses include genital herpes, cold sores, shingles, and chickenpox.Valtrex (VALACYCLOVIR) is used to treat cold sores in children who are at least 12 years old, and to treat chickenpox in children who are at least 2 years old.Valtrex (VALACYCLOVIR) may also be used for other purposes not listed in this medication guide.

Important information about Valtrex (VALACYCLOVIR)

Before taking Valtrex (VALACYCLOVIR), tell your doctor if you have HIV/AIDS, a weak immune system, kidney disease (or if you are on dialysis), or if you have had a kidney or bone marrow transplant. Valtrex (VALACYCLOVIR) can be harmful to the kidneys, and these effects are increased when it is used together with other medicines that can harm the kidneys.

Tell your doctor about all other medications you are using. You may need dose adjustments or special tests when taking certain medications together with Valtrex (VALACYCLOVIR).Treatment with Valtrex (VALACYCLOVIR) should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).Herpes virus can be passed from an infected mother to her baby during childbirth. If you have genital herpes, it is very important to prevent herpes lesions during your pregnancy so that you do not have a genital lesion when your baby is born.

Before taking Valtrex (VALACYCLOVIR)

Do not take this medicine if you are allergic to valacyclovir or acyclovir (Zovirax). If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking Valtrex (VALACYCLOVIR), tell your doctor if you have:HIV/AIDS, or other conditions that can weaken the immune system;kidney disease (or if you are on dialysis); orif you have had a kidney or bone marrow transplant.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. However, herpes virus can be passed from an infected mother to her baby during childbirth. If you have genital herpes, it is very important to prevent herpes lesions during your pregnancy so that you do not have a genital lesion when your baby is born. Valtrex (VALACYCLOVIR) passes into breast milk and may harm a nursing infant.

How should I take Valtrex (VALACYCLOVIR)?

Take Valtrex (VALACYCLOVIR) exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.Treatment with Valtrex (VALACYCLOVIR) should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). This medication might not be as effective if you first start taking it 1 or 2 days after the start of your symptoms.Take each dose with a full glass of water. Drink plenty of water while you are taking Valtrex (VALACYCLOVIR) to keep your kidneys working properly.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Valtrex (VALACYCLOVIR) will not treat a viral infection such as the common cold or flu. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.Store Valtrex (VALACYCLOVIR) tablets at room temperature away from moisture and heat.

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Store Valtrex (VALACYCLOVIR) liquid in a refrigerator. Do not freeze. Throw away any unused Valtrex (VALACYCLOVIR) that is older than 28 days.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include urinating less than usual or not at all.

What should I avoid while taking Valtrex (VALACYCLOVIR)?

Valtrex (VALACYCLOVIR) will not prevent the spread of genital herpes. Herpes infections are contagious and you can infect other people even while you are taking with Valtrex (VALACYCLOVIR).Avoid sexual intercourse or use a latex condom to prevent spreading the virus to others. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Side effects of Valtrex (VALACYCLOVIR):

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Valtrex (VALACYCLOVIR) and call your doctor right away if you have any of the following signs of a serious side effect that can harm red blood cells:fever, easy bruising or bleeding;red spots on the skin (not related to herpes or chickenpox);bloody diarrhea, vomiting;pale or yellowed skin;weakness or fainting; orurinating less than usual or not at all.

Less serious Valtrex (VALACYCLOVIR) side effects may include:

nausea, stomach pain;headache, dizziness, tired feeling, depression;jointpain;menstrualpain;mild skin rash; orstuffy nose, sore throat.This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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